Maintenance Treatment of Metastatic Pancreatic and Bile Duct Cancers with S-1 Has Provided Prolonged Oncologic Control and Quality of Life: Case Series

Case Series

Volume 5, Issue 6 (June Issue)

Maintenance Treatment of Metastatic Pancreatic and Bile Duct Cancers with S-1 Has Provided Prolonged Oncologic Control and Quality of Life: Case Series

Tsz Tong Raymond Chan^*

Private Practice, Honorary Associate Professor, Department of Oncology, The Chinese University of Hong Kong

^*Corresponding author: Tsz Tong Raymond Chan, Private Practice, Honorary Associate Professor, Department of Oncology, The Chinese University of Hong Kong, China. E-mail: chanttr062004@netvigator.com

Received: May 28, 2023; Accepted: June 12, 2023; Published: June 25, 2023

Citation: Chan TTR. Maintenance Treatment of Metastatic Pancreatic and Bile Duct Cancers with S-1 Has Provided Prolonged Oncologic Control and Quality of Life: Case Series. Clin Image Case Rep J. 2023; 5(6): 332.

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Maintenance Treatment of Metastatic Pancreatic and Bile Duct Cancers with S-1 Has Provided Prolonged Oncologic Control and Quality of Life: Case Series

Abstract

This case series covers three patients receiving S-1 maintenance therapy after resection and adjuvant chemotherapy for either metastatic pancreatic cancer (n = 2) or bile duct cancer (n = 1). In contrast to a standard S-1 regimen involving periodic two-week pauses, patients were administered with low-dose S-1 for 5 days every week without pause. All patients showed long-term remission for around three years or more. Furthermore, patients displayed notable quality of life despite continuous dosing. Therefore, in selected cases, S-1 may provide effective long-term oncologic maintenance without severe detriments to patient lifestyle.

Keywords: Case report; Oncology; Maintenance therapy; Metastatic pancreatic cancer; Bile duct cancer; S-1