Sarcomas are rare malignant neoplasms. They arise in tissues of mesenchymal origin. According to the World Health Organization, 80% of sarcomas arise from soft tissues, and the rest arise from the bone. In most cases of soft tissue sarcomas, the etiological factors remain unknown; however, many predisposing and associated factors have been established. These include genetic predispositions and mutations, chemotherapy, exposure to radiation, carcinogenic chemicals and viruses, and chronic irritation. Although injection-site sarcomas have been well-studied in animal models, no case of injection-site sarcoma has been reported in humans to the best of our knowledge. We report a case of injection-site soft tissue sarcoma with unique histology in a young male patient.