It was found that an important risk factor for recurrent thrombosis, coronary heart disease and cerebrovascular pathology is the level of acyl hydroperoxides in the blood. An analysis was made of the level of acyl hydroperoxides in patients with coronary heart disease with episodes of painless myocardial ischemia, as well as its correction with B vitamins. 84 patients with coronary heart disease with functional angina I-III were examined. It was found that a combination of a high level of acyl hydroperoxides and frequent episodes of painless myocardial ischemia is recorded mainly in patients with a high functional class of angina pectoris. The intake of B vitamins can significantly reduce the concentration of acyl hydroperoxides in the blood plasma and the frequency of episodes of painless myocardial ischemia. 
 
Keywords: Acyl hydroperoxides; Cardiology; Coronary heart disease; Angina pectoris; Painless ischemia