The Role of Celecoxib for Treatment of Isolated Fever in Schizophrenia: A Case Report and Literature Update on its Uses

Case Report

Volume 6, Issue 6 (June Issue)

The Role of Celecoxib for Treatment of Isolated Fever in Schizophrenia: A Case Report and Literature Update on its Uses

Evaristus Chino Ezema^1*, Nnenna Bessie Emejuru², Ogochukwu Agazie³, Sanmi Michael Obe⁴, Emmanuel Chiebuka⁵, Abdullah Y Hawsawi⁶, Ndukaku Ogbonna⁷, Chinwe Okeke-Moffatt⁸, Stephen Okorom⁹, Chinenye Loveth Aleke¹⁰, Vivien Obitulata Ugwu¹¹, Amogechukwu Onyinye Ugwu¹², Maureen Obi¹³, Tricia Okoye¹⁴and Chihurumnanya Precious Okpechi¹⁵

¹One Brooklyn Health, Brooklyn, NY, US
²College of Medicine, Imo State University, Nigeria
³College of Medicine, University of Lagos, Nigeria
⁴College of Medicine, Obafemi Awolowo University, Iloefe, Nigeria
⁵Kettering Health, Ohio
⁶Roosevelt University, Chicago, IL
⁷Dumont Center for Rehabilitation and Nursing Care, New Rochelle, NY
⁸Washington University of Health and Science, San Pedro, Belize
⁹Brooklyn Physicians, Brooklyn, NY, US
¹⁰Dept of Physiotherapy, Federal Medical Center, Makurdi, Benue State, Nigeria
¹¹College of Medicine, University of Nigeria, Nsukka, Nigeria
¹²University of Nigeria, Nsukka, Nigeria
¹³College of Medicine, Enugu State University, Nigeria
¹⁴Ambrose Alli University, Ekpoma, Nigeria
¹⁵School of Medicine, St. George’s University

^*Corresponding author: Evaristus Chino Ezema, One Brooklyn Health, Brooklyn, NY, US. E-mail: mceverz@yahoo.com

Received: May 16, 2024; Accepted: June 04, 2024; Published: June 15, 2024

Citation: Ezema EC, Emejuru NB, Agazie O, et al. The Role of Celecoxib for Treatment of Isolated Fever in Schizophrenia: A Case Report and Literature Update on its Uses. Clin Image Case Rep J. 2024; 6(6): 402.

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The Role of Celecoxib for Treatment of Isolated Fever in Schizophrenia: A Case Report and Literature Update on its Uses

Abstract

The occurrence of fever in schizophrenic patient can be transiently managed with either Tylenol or Ibuprofen, until the definitive cause of the fever is found. Pro-inflammatory cytokines which cause fever have been linked in the pathophysiology of schizophrenia, resulting in some instances of fever without known causes. Treatment options in patient allergic to both medications include the use of other non-steroidal anti-inflammatory drugs. Celecoxib proved effective in the treatment of fever in a patient with a diagnosis of multiple episodes of schizophrenia. Further review showed beneficial roles of Celecoxib in pain management, psychiatric disorders, and cancer treatment.

Keywords: Celecoxib; Fever; Role; Schizophrenia; Treatment