Introduction: In many cases, the combination diagnoses of scoliosis, lower back pain, sacroiliac dysfunction gets overlooked in physical therapy management. With available diagnostic tools to physical therapists, it has always been a challenge to diagnose and treat the condition appropriately and manage symptoms to improve quality of life.

Case Presentation and Treatment: A patient in her mid-20’s presented with mid and low back pain was managed conservatively utilizing specific mobilization/manipulation techniques, exercise regimen, home exercise program, orthotic modifications, and medications for a period of six months when patient was deemed non-surgical candidate.

Outcomes: Total of eighteen sessions of treatment was provided over the period of six months duration. The results of Numeric pain rating scale and Oswestry Disability questionnaire substantially decreased from 8/10 to 1/10 and 68% to 18% respectively.

Conclusion: Appropriate diagnosis and utilization of specific and combination of therapy to address specific dysfunction with home exercise program decreased pain and improved quality of life.

Keywords: Physical therapy; Sacroiliac dysfunction; Scoliosis; Lower back pain