A pacemaker-carrier 83-year-old female, with history of resected cervical carcinoma and anticoagulated atrial fibrillation, was admitted to the hospital due to severe acute anemia. Physical examination showed slight discomfort on deep palpation of the abdominal hypochondria. Complementary studies allowed the diagnosis of ileocecal angiectasia hemorrhage. After an inconclusive colonoscopy with insurmountable loop, an angiographic thoraco-abdominopelvic computed tomography was performed. The last found an inverted position of the infradiaphragmatic structures, with a left-quadrant liver(L) and a right-quadrant stomach (S) and spleen (Sp), next to small adjacent spleens. Situs inversus results from the disruption of the left-right axis orientation during early embryonic development, with a consequent mirror reverse arrangement of abdominal and thoracic structures. Cases of partial Situs inversus with levocardia are especially rare. Although not representing a health problem, these anatomical variants should be known as they can represent unexpected difficulties during certain therapeutic and diagnostic techniques.